I made a similar experience with the last CVS. (at least until CVS1109, which is in test)
the system crashed more or less regularly after running aMule for a while (time not always the same). With every half an hour aMule was running longer, the system got more and more overloaded and became slower until i had to wait for ~1 Minute to switch from stats-channel to download... this went on until aMule suddelny crashed.
i don't know if that's also a memory issue or another one, but it somehow seemed to me, that aMule was somehow overloading the RAM until its crash.
another point I saw is, that before its crash, download and upload rates began to fall to very low rates. Specially the upload rate should behave stable, so always when I see these signs I know that sooner or later, aMule is going to crash. This behaviour was stable with CVS 0308.
Regards
Alvaro