I dont hink so...
its only a problem if you have 2 or more wx-config on your system
for example
/usr/bin/
and
/usr/local/bin/
this is when you need --with-wx-config...to tell configure which one to use, otherwise it will always use the one from
/usr/bin/
btw, could it be you mabye miss a pkg for wxGTK which includes the .h (header) files??
since those seam to be missing in your installation.
stefanero