We're back! (IN POG FORM)
So first you need to start Terminal (in /Applications/Utilities/). Then drag the aMule application icon from wherever you keep it and drop it onto the Terminal window. Terminal will insert the path to the application onto the command line. It will also add a space after the path. Now delete the space at the end of the path and paste /Contents/MacOS/amule to the end of the path. When you then press return aMule will start.