well, when such problems happen, the best is to rename ~/.aMule and ~/.eMule and restart aMule. Then, if it works, try to rename back to the original names file-by-file so you know which file is failing.
Anyway, v2-RC3 is out and is incredibly-far-much-less buggy than RC2, so I guess you should try with RC3 rather than with Rc2 (and, btw, it comes with full OpenBSD support). Alos, you'll benefit from the rewritten net code, which is far much quicker on transfering than RC2.
So, conclusion, compile rc3 ;-)
Greetings.